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anti-GRIN1 antibody product blog

Posted on 2018-10-12 12:21:03 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-GRIN1 antibody; GRIN1; GRIN1 / NMDAR1;
The GRIN1 grin1 (Catalog #MBS242755) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human GRIN1 / NMDAR1 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GRIN1 / NMDAR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).
ELISA (1:20000), IHC-P (10 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the GRIN1 grin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The GRIN1 grin1 product has the following accession number(s) (GI #11038637) (NCBI Accession #NP_015566.1) (Uniprot Accession #Q05586). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal (IgG) to Human GRIN1 / NMDAR1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-GRIN1 / NMDAR1 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC) GRIN1.

Western Blot (WB) (Western blot of extracts from Jurkat cells, using NMDAR1 antibody. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB) GRIN1.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR).

Target Species: Human
Immunogen Description: Synthetic peptide from human NMDAR1 (aa864-913). Immunogen: GRIN1 / NMDAR1 antibody was raised against synthetic peptide from human NMDAR1 (aa864-913).
Antigen Modification: aa864-913. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GRIN1 are readily searchable from our website. Different antibodies against the same target such as GRIN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Depressive Disorder, Disease Models, Animal, Learning Disorders, Memory Disorders, Movement Disorders, Nerve Degeneration, Nervous System Diseases, Pain, Poisoning are some of the diseases may be linked to Rabbit Polyclonal (IgG) to Human GRIN1 / NMDAR1. The following patways have been known to be associated with this gene.
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