anti-GRM1 antibody product blog
Tags: Antibody; Polyclonal Antibody; GRM1 / MGLUR1; anti-GRM1 antibody; GRM1;
The GRM1 grm1 (Catalog #MBS244218) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GRM1 / MGLUR1 reacts with Gibbon, Chimpanzee, Gorilla, Human, MonkeyPredicted Reactivity: Mouse, Rat, Bat, Dog, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s GRM1 / MGLUR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (14 - 28 ug/ml). Researchers should empirically determine the suitability of the GRM1 grm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GRM1 grm1 product has the following accession number(s) (GI #166999098) (NCBI Accession #NP_000829.2) (Uniprot Accession #Q13255). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human GRM1 / MGLUR1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-GRM1 / MGLUR1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
The Metabotropic Glutamate Receptor mGluR1 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. mGluR1 and mGluR5 are group I receptors that have been shown to activate phospholipase C.
Target Species: Human
Immunogen Description: Synthetic 16 amino acid peptide from C-terminus of human GRM1 / MGLUR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%). Immunogen Type: Synthetic peptide
Immunogen: GRM1 / MGLUR1 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human GRM1 / MGLUR1. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Rabbit, Horse (94%); Opossum, Chicken, Platypus (88%); Bovine, Xenopus (81%).
Antigen Modification: C-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GRM1 are readily searchable from our website. Different antibodies against the same target such as GRM1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Attention Deficit Disorder with Hyperactivity, Brain Diseases, Cognition Disorders, Disease Models, Animal, Epilepsy, Fibroma, Movement Disorders, Nervous System Diseases, Prenatal Exposure Delayed Effects, Tremor are some of the diseases may be linked to Rabbit Polyclonal to Human GRM1 / MGLUR1.