anti-GRM1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GRM1 antibody; GRM1; mGluR1a;
The GRM1 grm1 (Catalog #MBS621246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The mGluR1a (Metabotropic Glutamate Receptor 1 alpha, mGluR1alpha, G Protein Coupled Receptor Family C Group 1 Member A, GPRC1A, Glutamate Receptor Metabotropic 1 alpha, GRM1A, Human Metabotropic Glutamate Receptor 1 alpha mRNA Complete cds) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s mGluR1a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 1:100-1:500
Western Blot: 1:500-1:1000
Storage and Stability:
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 3 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Researchers should empirically determine the suitability of the GRM1 grm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GRM1 grm1 product has the following accession number(s) (GI #493799345) (NCBI Accession #NP_001264995.1) (Uniprot Accession #Q13255). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the mGluR1a (Metabotropic Glutamate Receptor 1 alpha, mGluR1alpha, G Protein Coupled Receptor Family C Group 1 Member A, GPRC1A, Glutamate Receptor Metabotropic 1 alpha, GRM1A, Human Metabotropic Glutamate Receptor 1 alpha mRNA Complete cds) with the following immunoassay(s):
Testing Data
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Immunogen: Synthetic peptide comprising internal residues of the human GluR1 alpha protein.