anti-GRM8 antibody product blog
Tags: Antibody; Polyclonal Antibody; Grm8; anti-GRM8 antibody; Metabotropic Glutamate Receptor 8;
The GRM8 grm8 (Catalog #MBS9214932) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Metabotropic Glutamate Receptor 8 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. MyBioSource\'s Metabotropic Glutamate Receptor 8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the GRM8 grm8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GRM8 grm8 product has the following accession number(s) (GI #187960067) (NCBI Accession #NP_000836.2) (Uniprot Accession #O00222). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Metabotropic Glutamate Receptor 8 Antibody (C-term) with the following immunoassay(s):
Western Blot (WB) (The GRPRC1H C-term Pab is used in Western blot to detect GRPRC1H in mouse brain tissue lysate.)
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors,
that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7
and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GRM8 are readily searchable from our website. Different antibodies against the same target such as GRM8 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Attention Deficit Disorder with Hyperactivity, Autistic Disorder, Brain Diseases, Cognition Disorders, Eye Abnormalities, Learning Disorders, Lung Neoplasms, Mental Disorders, Microcephaly, Weight Gain are some of the diseases may be linked to Metabotropic Glutamate Receptor 8 Antibody (C-term).