anti-GSTP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; GSTP1; anti-GSTP1 antibody;
The GSTP1 gstp1 (Catalog #MBS9406574) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GSTP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s GSTP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GSTP1 gstp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The GSTP1 gstp1 product has the following accession number(s) (GI #4504183) (NCBI Accession #NP_000843). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GSTP1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of GSTP1 in Jurkat cell lysate with GSTP1 antibody at (A) 0.5 and (B) 1 ug/mL.)
Immunohistochemistry (IHC) (Immunohistochemical staining of human lung tissue using GSTP1 antibody at 2.5 ug/mL.)
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson\'s disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.
Immunogen Type: Peptide
Immunogen Description: Raised against a 14 amino acid peptide from near the center of human GSTP1. Target Name: GSTP1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GSTP1 are readily searchable from our website. Different antibodies against the same target such as GSTP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.