anti-GUCA2B antibody product blog
Tags: Antibody; Polyclonal Antibody; GUCA2B; anti-GUCA2B antibody;
The GUCA2B guca2b (Catalog #MBS9128206) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GUCA2B Polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s GUCA2B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).WB 1:500 - 1:2000. Researchers should empirically determine the suitability of the GUCA2B guca2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GUCA2B guca2b product has the following accession number(s) (GI #6005774) (NCBI Accession #NP_009033.1) (Uniprot Accession #Q16661). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the GUCA2B Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of mouse small intestine, using GUCA2B antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.)
This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues.
Route: Synthetic Peptide. Immunogen: A synthetic peptide of human GUCA2B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GUCA2B are readily searchable from our website. Different antibodies against the same target such as GUCA2B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Cardiovascular Diseases, Hypertension, Inflammation, Necrosis, Prenatal Exposure Delayed Effects are some of the diseases may be linked to GUCA2B Polyclonal Antibody. Intestine tissues are correlated with this protein. The following patways have been known to be associated with this gene. GUCA2B also interacts with the following gene(s): GUCY2C.