anti-HAMP antibody product blog
Tags: Antibody; Polyclonal Antibody; HAMP; anti-HAMP antibody;
The HAMP hamp (Catalog #MBS9408123) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HAMP antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s HAMP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western blotting: 1:500 - 1:2000. Researchers should empirically determine the suitability of the HAMP hamp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HAMP hamp product has the following accession number(s) (GI #10863973) (NCBI Accession #NP_066998.1) (Uniprot Accession #P81172). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HAMP antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of MB435 cell lines, using HAMP antibody.)
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
Immunogen Type: Recombinant Protein
Immunogen Description: Recombinant protein of human HAMP. Target Name: HAMP
SDS-PAGE MW: 9kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HAMP are readily searchable from our website. Different antibodies against the same target such as HAMP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Anemia, Cardiovascular Diseases, Disease Models, Animal, Hemochromatosis, Inflammation, Iron Overload, Kidney Diseases, Liver Diseases, Necrosis, beta-Thalassemia are some of the diseases may be linked to HAMP antibody. The following patways have been known to be associated with this gene. Brain, Eye, Liver, Lung, Placenta, Spleen tissues are correlated with this protein.