anti-HIF1A antibody product blog
Tags: Antibody; Polyclonal Antibody; HIF1A; anti-HIF1A antibody;
The HIF1A hif1a (Catalog #MBS2528262) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HIF1A Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s HIF1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).WB: 1:500-1:2000. Researchers should empirically determine the suitability of the HIF1A hif1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HIF1A hif1a product has the following accession number(s) (GI #2498017) (NCBI Accession #Q16665.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HIF1A Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Untreated and treated with cobalt chloride (0.1 mM for 4 hours) of hela cell using HIF1A Polyclonal Antibody at dilution of 1:400)
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.
Immunogen: Synthetic peptide of human HIF1A
Calculated Molecular Weight: 93kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HIF1A are readily searchable from our website. Different antibodies against the same target such as HIF1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. HIF1A also interacts with the following gene(s): ARNT, CREBBP, EGLN1, EGLN3, EP300, HIF1AN, HSP90AA1, TP53, UBC, VHL. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Carcinoma, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to HIF1A Polyclonal Antibody.