anti-HIST1H2BJ antibody product blog
Tags: Antibody; Polyclonal Antibody; HIST1H2BJ; anti-HIST1H2BJ antibody; HIST1H2BJ/HIST1H2BK/HIST3H2BB;
The HIST1H2BJ hist1h2bj (Catalog #MBS9201580) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) reacts with Human (Predicted Reactivity: Xenopus, Bovine, Monkey, Mouse) and may cross-react with other species as described in the data sheet. MyBioSource\'s HIST1H2BJ/HIST1H2BK/HIST3H2BB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the HIST1H2BJ hist1h2bj for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HIST1H2BJ hist1h2bj product has the following accession number(s) (GI #20336754) (NCBI Accession #NP_066402.2) (Uniprot Accession #P06899). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) with the following immunoassay(s):
Western Blot (WB) (HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).)
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the histone microcluster on chromosome 6p21.33. [provided
by RefSeq].
Calculated MW: 13904. Function: Core component of nucleosome.Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to thecellular machineries which require DNA as atemplate. Histones thereby play a central rolein transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HIST1H2BJ are readily searchable from our website. Different antibodies against the same target such as HIST1H2BJ may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.