anti-HMGCL antibody product blog
Tags: Antibody; Polyclonal Antibody; HMGCL; anti-HMGCL antibody;
The HMGCL hmgcl (Catalog #MBS9211032) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMGCL Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HMGCL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the HMGCL hmgcl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HMGCL hmgcl product has the following accession number(s) (GI #62198232) (NCBI Accession #NP_000182.2) (Uniprot Accession #P35914). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HMGCL Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (HMGCL Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the HMGCL antibody detected the HMGCL protein (arrow).)
The protein encoded by this gene belongs to the HMG-CoA
lyase family. It is a mitochondrial enzyme that catalyzes the final
step of leucine degradation and plays a key role in ketone body
formation. Mutations in this gene are associated with HMG-CoA lyase
deficiency. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HMGCL are readily searchable from our website. Different antibodies against the same target such as HMGCL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, Breast Neoplasms, Disease Models, Animal, Fatty Liver, Inflammation, Liver Diseases, Nervous System Diseases are some of the diseases may be linked to HMGCL Antibody (N-term). The following patways have been known to be associated with this gene. HMGCL also interacts with the following gene(s): ACAT1, BDH1, HMGCS1, HMGCS2, OXCT1. Adipose Tissue, Blood, Brain, Connective Tissue, Heart, Kidney, Liver, Muscle, Prostate, Skin tissues are correlated with this protein.