anti-Hsc70 antibody product blog
Tags: Antibody; Polyclonal Antibody; HSC70; anti-Hsc70 antibody;
The Hsc70 hspa8 (Catalog #MBS841011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Hsc70 Antibody reacts with Human, Mouse, Rat, Monkey, Hamster, Rabbit, Bovine and may cross-react with other species as described in the data sheet. MyBioSource\'s Hsc70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blot analysis (0.5-4 ug/ml) and in Immunohistochemistry. However, the optimal conditions should be determined individually. The antibody detects a 71 kDa Hsc70. A ~40 kDa band can also be detected in human samples. Jurkat cell lysate and mouse small intestine lysate can be used as positive controls. Researchers should empirically determine the suitability of the Hsc70 hspa8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Hsc70 hspa8 product has the following accession number(s) (GI #5729877) (NCBI Accession #NP_006588.1) (Uniprot Accession #P11142). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Hsc70 Antibody with the following immunoassay(s):
Testing Data
Background: The 70 kDa heat shock cognate protein, Hsc70, is part of the Hsp70 family. The family includes both cognate members and highly inducible isoforms. Members of the Hsp70 family are molecular chaperones which are involved in many cellular functions such as protein folding, transport, maturation and degradation.
Immunogen: Synthetic peptide surrounding amino acid 559 of human Hsc70. Handling: The antibody solution should be gently mixed before use. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Hsc70 are readily searchable from our website. Different antibodies against the same target such as Hsc70 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Nerve, Vascular tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Heart Diseases, Inflammation, Liver Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Hsc70 Antibody. The following patways have been known to be associated with this gene.