anti-HSD11B1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-HSD11B1 antibody; HSD11B1; Corticosteroid 11-beta-dehydrogenase isozyme 1;
The HSD11B1 hsd11b1 (Catalog #MBS7002887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Corticosteroid 11-beta-dehydrogenase isozyme 1 polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Corticosteroid 11-beta-dehydrogenase isozyme 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the HSD11B1 hsd11b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HSD11B1 hsd11b1 product has the following accession number(s) (GI #332078483) (NCBI Accession #NP_001193670.1) (Uniprot Accession #P28845). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-human Corticosteroid 11-beta-dehydrogenase isozyme 1 polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody at 2ug/ml+Hela cells
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 32kDa
Observed band size: 32kDa
)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland using MBS7002887 at dilution 1:100)
Immunohistochemistry (IHC) (Immunofluorescent analysis of Hela cells using MBS7002887 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.
This protein is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Immunogen: Recombinant human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein(25-292aa). Conjugation: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19259 / sc-19257 / sc-20175. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HSD11B1 are readily searchable from our website. Different antibodies against the same target such as HSD11B1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.