anti-HSD17B10 antibody product blog
Tags: Antibody; Polyclonal Antibody; HSD17B10; anti-HSD17B10 antibody; 3-hydroxyacyl-CoA dehydrogenase type-2;
The HSD17B10 hsd17b10 (Catalog #MBS7003071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human 3-hydroxyacyl-CoA dehydrogenase type-2 polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s 3-hydroxyacyl-CoA dehydrogenase type-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Recommended dilution: WB:1:500-2000. Researchers should empirically determine the suitability of the HSD17B10 hsd17b10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HSD17B10 hsd17b10 product has the following accession number(s) (GI #83715985) (NCBI Accession #NP_001032900.1) (Uniprot Accession #Q99714). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-human 3-hydroxyacyl-CoA dehydrogenase type-2 polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: 3-hydroxyacyl-CoA dehydrogenase type-2 antibody at 2ug/ml
Lane 1:mouse brain tissue
Lane 2:293T whole cell lysate
Lane 3:HepG2 whole cell lysate
Lane 4:Hela whole cell lysate
Lane 5:HT29 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 27,26 kDa
Observed band size: 27 kDa
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Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5\'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Immunogen: Recombinant human 3-hydroxyacyl-CoA dehydrogenase type-2 protein(2-261aa). Conjugation: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7689 / sc-7690. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HSD17B10 are readily searchable from our website. Different antibodies against the same target such as HSD17B10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.