anti-HTR1B antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-HTR1B antibody; HTR1B; HTR1B / 5-HT2B Receptor;
The HTR1B htr2b (Catalog #MBS246779) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human HTR1B / 5-HT2B Receptor reacts with Gibbon, Chimpanzee, Gorilla, Human, Monkey, Orangutan and may cross-react with other species as described in the data sheet. MyBioSource\'s HTR1B / 5-HT2B Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).IHC-P (2 ug/ml). Researchers should empirically determine the suitability of the HTR1B htr2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HTR1B htr2b product has the following accession number(s) (GI #222080049) (NCBI Accession #NP_000858.3) (Uniprot Accession #P41595). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human HTR1B / 5-HT2B Receptor with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-5HT2B Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood; mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation.
Target Species: Human
Immunogen Description: Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human 5HT2B Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Bovine, Rabbit, Pig (88%). Immunogen Type: Synthetic peptide
Immunogen: HTR1B / 5-HT2B Receptor antibody was raised against synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human 5HT2B Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%); Bovine, Rabbit, Pig (88%); Dog, Bat, Panda, Horse, Opossum, Stickleback (82%).
Antigen Modification: Cytoplasmic Domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HTR1B are readily searchable from our website. Different antibodies against the same target such as HTR1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.