|The HTR1B htr1b (Catalog #MBS645525) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HTR1B, ID (HTR1B, HTR1DB, 5-hydroxytryptamine receptor 1B, S12, Serotonin 1D beta receptor, Serotonin receptor 1B) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HTR1B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500. Researchers should empirically determine the suitability of the HTR1B htr1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HTR1B htr1b product has the following accession number(s) (GI #66365832) (NCBI Accession #AAH96206.1) (Uniprot Accession #P28222). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.
Immunogen: HTR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human HTR1B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HTR1B are readily searchable from our website. Different antibodies against the same target such as HTR1B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. HTR1B also interacts with the following gene(s): ADRA2A, DRD2, DRD4, HTR1A, HTR1D, HTR5A, NPY. The following patways have been known to be associated with this gene. Anxiety Disorders, Brain Diseases, Depressive Disorder, Headache, Hypothermia, Mental Disorders, Migraine Disorders, Mood Disorders, Nervous System Diseases, Pain are some of the diseases may be linked to HTR1B, ID (HTR1B, HTR1DB, 5-hydroxytryptamine receptor 1B, S12, Serotonin 1D beta receptor, Serotonin receptor 1B).