anti-HYAL1 antibody product blog
Tags: Antibody; HYAL1; Polyclonal Antibody; anti-HYAL1 antibody;
The HYAL1 hyal1 (Catalog #MBS176784) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HYAL1 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HYAL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC. Researchers should empirically determine the suitability of the HYAL1 hyal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The HYAL1 hyal1 product has the following accession number(s) (GI #74735617) (NCBI Accession #Q12794.2) (Uniprot Accession #Q12794). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-HYAL1 antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-HYAL1 antibody, MBS176784, IHC(P)
IHC(P): Human Intestinal Cancer Tissue )
Immunocytochemistry (ICC) (Anti-HYAL1 antibody, MBS176784, ICC
ICC: MCF-7 Cell )
Western Blot (WB) (Anti-HYAL1 antibody, MBS176784, Western blotting
Lane 1: HELA Cell Lysate
Lane 2: 22RV1 Cell Lysate
Lane 3: MCF-7 Cell Lysate
)
Immunohistochemistry (IHC) (Anti-HYAL1 antibody, MBS176784, IHC(F)
IHC(F): Human Placenta Tissue )
Description: Rabbit IgG polyclonal antibody for Hyaluronidase-1(HYAL1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
Background: Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HYAL1 (32-47aa FTTVWNANTQWCLERH). Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HYAL1 are readily searchable from our website. Different antibodies against the same target such as HYAL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.