|The IGF1R igf1r (Catalog #MBS2522014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IGF1R (Ab-1165/1166) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IGF1R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1000. Researchers should empirically determine the suitability of the IGF1R igf1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IGF1R igf1r product has the following accession number(s) (GI #4557665) (NCBI Accession #NP_000866.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IGF1R (Ab-1165/1166) Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of 293 cells using IGF1R (Ab-1165/1166) Polyclonal Antibody at dilution of 1:500)
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.
Immunogen: Synthetic peptide of human IGF1R (Ab-1165/1166)
Calculated Molecular Weight: 155kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IGF1R are readily searchable from our website. Different antibodies against the same target such as IGF1R may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. IGF1R also interacts with the following gene(s): ESR1, GRB10, IGF1, IGF2, IRS1, IRS2, PIK3R1, PTPN11, SHC1, UBC. Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Prostate, Vascular tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Cell Transformation, Neoplastic, Disease Models, Animal, Growth Disorders, Insulin-Like Growth Factor I, Resistance To, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to IGF1R (Ab-1165/1166) Polyclonal Antibody.