anti-IKB alpha antibody product blog
Tags: Antibody; Polyclonal Antibody; IkB alpha; anti-IkB alpha antibody;
The IKB alpha n/a (Catalog #MBS835603) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s IKB alpha can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB).IHC: 1:50-1:100
WB: 1:500-1:1000. Researchers should empirically determine the suitability of the IKB alpha n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IKB alpha antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of extract from Hela cells and MDA cells using IkappaB-alpha (Phospho-Tyr42) antibody)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkappaB-alpha (Phospho-Tyr42) antibody)
Rabbit polyclonal IKB alpha antibody.
Biological Significance: IkB-alpha a regulatory protein that inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. May be involved in regulation of transcriptional responses to NF-kappa-B, including cell adhesion, immune and proinflammatory responses, apoptosis, differentiation and growth. Controlled by sequential serine-phosphorylation, ubiquitination and degradation. Cross-Reactivity: Human, Mouse, Rat
Immunogen: IKB alpha antibody was raised in Rabbit using the peptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IKB-An as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IKB alpha are readily searchable from our website. Different antibodies against the same target such as IKB alpha may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.