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anti-IKBKG antibody product blog

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Posted on 2015-07-26 21:00:50 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; IKBKG; anti-IKBKG antibody; KK gamma;
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The IKBKG ikbkg (Catalog #MBS175365) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-KK gamma antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s KK gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IKBKG ikbkg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The IKBKG ikbkg product has the following accession number(s) (GI #341941165) (NCBI Accession #O88522.2) (Uniprot Accession #O88522). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-KK gamma antibody with the following immunoassay(s):
Western Blot (WB) (Anti-IKK gamma antibody, MBS175365, Western blotting
Lane 1: Mouse Liver Tissue Lysate
Lane 2: Mouse Brain Tissue Lysate
Lane 3: Mouse Ovary Tissue Lysate
)
Western Blot (WB) IKBKG.

Description: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.
Background: IKBKG(Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, gamma) is also known as NEMO. The IKK complex is composed of IKK-alpha, IKK-beta, and 2 other polypeptides of 50 and 52 kD which are differentially processed forms of a third subunit, IKK-gamma. The 419-amino acid IKK-gamma protein is composed of several potential coiled-coil motifs and a leucine zipper motif. NEMO interacted with IKK2(IKK-beta), but not with IKK1(IKK-alpha). IKK-gamma forms dimers and trimers and interacts preferentially with IKK-beta.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse KK gamma (1-15aa MNKHPWKNQLSEMVQ), different from the relative rat sequence by three amino acids. Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IKBKG are readily searchable from our website. Different antibodies against the same target such as IKBKG may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Incontinentia Pigmenti, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to Anti-KK gamma antibody.
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