anti-IKK-gamma antibody product blog
Tags: Antibody; Polyclonal Antibody; IKK-gamma; anti-IKK-gamma antibody;
The IKK-gamma ikbkg (Catalog #MBS9409890) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKK-gamma (Phospho-Ser31) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IKK-gamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western blotting: 1:500~1:1000. Researchers should empirically determine the suitability of the IKK-gamma ikbkg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IKK-gamma ikbkg product has the following accession number(s) (GI #223671870) (NCBI Accession #NP_001093326.2) (Uniprot Accession #Q9Y6K9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IKK-gamma (Phospho-Ser31) Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from 293 cells treated with TNF-an using Phospho-IKK- gamma (Ser31) antibody.The lane on the right is treated with the antigen-specific peptide.)
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either \'Lys-63\'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Carter RS, Pennington KN, Ungurait BJ, Ballard DW (2003)J Biol Chem 278, 19642-8.
Immunogen Type: Peptide-KLH
Immunogen Description: Peptide sequence around phosphorylation site of serine 31 (E-E-S(p)-P-L) derived from Human IKK-gamma. Modification: Phospho-Ser31
Target Name: IKK- gamma. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IKK-gamma are readily searchable from our website. Different antibodies against the same target such as IKK-gamma may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. IKK-gamma also interacts with the following gene(s): BCL10, CHUK, CYLD, IKBKB, NFKBIA, RIPK1, SUMO1, TRAF6, UBC. Blood, Bone, Brain, Embryonic Tissue, Eye, Kidney, Liver, Lung, Lymph Node, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Hepatocellular, Disease Models, Animal, Incontinentia Pigmenti, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to IKK-gamma (Phospho-Ser31) Antibody.