|The IL10 il10 (Catalog #MBS175362) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-mouse IL10 antibody reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IL10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the IL10 il10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL10 il10 product has the following accession number(s) (GI #408360145) (NCBI Accession #P18893.2) (Uniprot Accession #P18893). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-mouse IL10 antibody with the following immunoassay(s):
Western Blot (WB) (Anti-mouse IL-10 antibody, MBS175362, Western blotting
Lane 1: Recombinant Mouse IL-10 Protein 10ng
Lane 2: Recombinant Mouse IL-10 Protein 5ng
Lane 3: Recombinant Mouse IL-10 Protein 2 )
Description: Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB, ELISA in Mouse.
Background: Interleukin-10(IL-10 or IL10), also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al.(1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al.(1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Immunogen: E Coli-derived mouse IL-10 recombinant protein (Position: S19-S178). Contents: Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL10 are readily searchable from our website. Different antibodies against the same target such as IL10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Arthritis, Rheumatoid, Colitis, Genetic Predisposition to Disease, HIV Infections, Hypersensitivity, Immediate, Inflammation, Inflammatory Bowel Diseases, Kidney Diseases, Necrosis, Sepsis are some of the diseases may be linked to Anti-mouse IL10 antibody.