anti-IL1R1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-IL1R1 antibody; IL1R1; Interleukin-1 receptor type 1;
The IL1R1 il1r1 (Catalog #MBS1498887) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Interleukin-1 receptor type 1 polyclonal Antibody(IL1R1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Interleukin-1 receptor type 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).Recommended dilution: WB:1:500-2000
IHC:1:20-1:200. Researchers should empirically determine the suitability of the IL1R1 il1r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL1R1 il1r1 product has the following accession number(s) (GI #4504659) (NCBI Accession #NP_000868.1) (Uniprot Accession #P14778). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti-human Interleukin-1 receptor type 1 polyclonal Antibody(IL1R1) with the following immunoassay(s):
Western Blot (WB) (All lanes: Interleukin-1 receptor type 1 antibody at 6ug/ml
Lane 1:Hela whole cell lysate
Lane 2:mouse heart tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 65kDa
Observed band size: 65kDa
)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney using MBS1498887 at dilution 1:100)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta using MBS1498887 at dilution 1:100)
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate: Non-conjugated. Immunogen: Recombinant human Interleukin-1 receptor type 1 protein (18-320aa)
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-688 / sc-25775 / sc-687. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL1R1 are readily searchable from our website. Different antibodies against the same target such as IL1R1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.