anti-IL36RN antibody product blog
Tags: Antibody; Polyclonal Antibody; IL36RN; anti-IL36RN antibody; IL-36RN;
The IL36RN il36rn (Catalog #MBS153357) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL-36RN Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IL-36RN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).IL-36RN antibody can be used for detection of IL-36RN by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the IL36RN il36rn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL36RN il36rn product has the following accession number(s) (GI #27894310) (NCBI Accession #NP_775262) (Uniprot Accession #Q9UBH0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IL-36RN Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of IL-36RN in human spleen tissue lysate with IL-36RN antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC) (Immunohistochemistry of IL-36RN in rat small intestine tissue with IL-36RN antibody at 5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of IL-36RN in rat small intestine tissue with IL-36RN antibody at 20 μg/mL.)
IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).
Conjugate: Unconjugated
Immunogen: IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN.
Buffer: IL-36RN antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL36RN are readily searchable from our website. Different antibodies against the same target such as IL36RN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.