|The INA ina (Catalog #MBS835849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The alpha Internexin antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s alpha Internexin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1000. Researchers should empirically determine the suitability of the INA ina for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INA ina product has the following accession number(s) (GI #14249342) (NCBI Accession #NP_116116.1) (Uniprot Accession #Q16352). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the alpha Internexin antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of extract from Rat brain and Rat hippocampus Tissue using a-lnternexin antibody)
Rabbit polyclonal alpha Internexin antibody.
Biological Significance: alpha-Internexin, is a Class IV intermediate filament approximately 66 KDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the Central Nervous System of adults. The protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers. Immunogen: alpha Internexin antibody was raised in Rabbit using the peptide sequence around aa 491~495(E-T-T-I-S)derived from Human A-Internexin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INA are readily searchable from our website. Different antibodies against the same target such as INA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Eye, Ganglia, Heart, Intestine, Kidney, Liver, Lung, Muscle, Nerve tissues are correlated with this protein. INA also interacts with the following gene(s): NEFH, NEFM. Brain Diseases, Cardiovascular Diseases, Congenital Abnormalities, Hypertension, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to alpha Internexin antibody.