|The INHA inha (Catalog #MBS540605) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Inhibin alpha Antibody Affinity Purified reacts with Human, 78% homology with mouse protein and may cross-react with other species as described in the data sheet. MyBioSource\'s Inhibin alpha can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB).
Confocal Microscopy: 1:200
Dot Blot: 1:20,000
Western Blot: 1:500. Researchers should empirically determine the suitability of the INHA inha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INHA inha product has the following accession number(s) (GI #124274) (NCBI Accession #P05111.1) (Uniprot Accession #P05111). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity Purified Inhibin alpha chain; Flags Antibody Mid Region
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone.
Immunogen: Synthetic peptide taken within amino acid region 125-175 on human alpha Inhibin.
Expression: Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins An and B are found in female. Determinant: Mid Region
Molecular Function: Cytokine activity, hormone activity, growth factor activity, receptor binding
Subcellular Location: Secreted. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INHA are readily searchable from our website. Different antibodies against the same target such as INHA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. INHA also interacts with the following gene(s): ACVR2A, CGA, FSHB, FST, INHBA, INHBB, INHBC, INHBE, TGFBR3. Diabetes Mellitus, Disease Models, Animal, Genital Diseases, Male, Heart Diseases, Hypertension, Inflammation, Liver Diseases, Necrosis, Nervous System Diseases, Pain are some of the diseases may be linked to Inhibin alpha Antibody Affinity Purified.