anti-INS antibody product blog
Tags: Antibody; Insulin; INS; Polyclonal Antibody; anti-INS antibody;
The INS ins (Catalog #MBS840328) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Insulin Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Insulin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Researchers should empirically determine the suitability of the INS ins for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INS ins product has the following accession number(s) (GI #4557671) (NCBI Accession #NP_000198.1) (Uniprot Accession #P01308). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Insulin Antibody with the following immunoassay(s):
Testing Data
Background: Insulin is important in stimulating the uptake of glucose from blood in the skeletal muscle and adipose tissue. It is secrered by pancreatic beta cells thromugh a glucose sensing pathway. Insulin also increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin is first formed as a precursor molecule, preproinsulin which is then processed into proinsulin and finally to the mature insulin hormone. A mature form of insulin has an A chain and a B chain that are connnected by two dilsufide bonds. Defects in insulin are the cause of type-II diabetes mellitus.
Immunogen: E. coli expressed recombinant human Insulin. Handling: The antibody solution should be gently mixed before use. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INS are readily searchable from our website. Different antibodies against the same target such as INS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. INS also interacts with the following gene(s): AKT1, FOXO1, IGF1R, IGFBP1, INSR, IRS1, IRS2, PDX1. Blood, Bone, Brain, Heart, Kidney, Liver, Muscle, Nerve, Pancreas, Vascular tissues are correlated with this protein. Diabetes Mellitus, Diabetes Mellitus, Type 2, Hyperglycemia, Hyperinsulinism, Hypertension, Hypoglycemia, Insulin Resistance, Metabolic Diseases, Obesity, Polycystic Ovary Syndrome are some of the diseases may be linked to Insulin Antibody. The following patways have been known to be associated with this gene.