anti-IRF4 antibody product blog
Tags: Antibody; IRF4; Polyclonal Antibody; anti-IRF4 antibody;
The IRF4 irf4 (Catalog #MBS2522424) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IRF4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IRF4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).WB: 1:200-1:1000. Researchers should empirically determine the suitability of the IRF4 irf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IRF4 irf4 product has the following accession number(s) (GI #305632828) (NCBI Accession #NP_001182215.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IRF4 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of Mouse lung tissue using IRF4 Polyclonal Antibody at dilution of 1:300)
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6; 14)(p25; q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Immunogen: Synthetic peptide of human IRF4
Calculated Molecular Weight: 52kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IRF4 are readily searchable from our website. Different antibodies against the same target such as IRF4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Eye, Heart, Kidney, Lung, Lymph, Lymph Node, Pharynx, Skin, Spleen tissues are correlated with this protein. Cell Transformation, Neoplastic, Colitis, Disease Models, Animal, Hyperplasia, Inflammation, Leukemia, Lymphocytic, Chronic, B-Cell, Multiple Myeloma, Necrosis, Neoplasms, Experimental, Skin Neoplasms are some of the diseases may be linked to IRF4 Polyclonal Antibody.