|The IRF6 irf6 (Catalog #MBS2524084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IRF6 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IRF6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the IRF6 irf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IRF6 irf6 product has the following accession number(s) (GI #331999978) (NCBI Accession #NP_001193625.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IRF6 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of 231 cell, Mouse kidney and lung tissue using IRF6 Polyclonal Antibody at dilution of 1:400)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer using IRF6 Polyclonal Antibody at dilution of 1:50)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer using IRF6 Polyclonal Antibody at dilution of 1:50)
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Immunogen: Recombinant protein of human IRF6
Calculated Molecular Weight: 53kDa. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IRF6 are readily searchable from our website. Different antibodies against the same target such as IRF6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Cardiovascular Diseases, Cleft Lip, Cleft Palate, Craniofacial Abnormalities, Limb Deformities, Congenital, OROFACIAL CLEFT 6, SUSCEPTIBILITY TO, Popliteal Pterygium Syndrome, Skin Abnormalities, Urogenital Abnormalities, Van der Woude syndrome are some of the diseases may be linked to IRF6 Polyclonal Antibody. IRF6 also interacts with the following gene(s): CD44, IRF2, IRF5, IRF8.