anti-ITM2B antibody product blog
Tags: Antibody; Polyclonal Antibody; ITM2B; anti-ITM2B antibody; Integral Membrane Protein 2B;
The ITM2B itm2b (Catalog #MBS612937) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The Integral Membrane Protein 2B (ITM2B, BRICHOS Domain Containing 2B) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Integral Membrane Protein 2B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:2000. Researchers should empirically determine the suitability of the ITM2B itm2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ITM2B itm2b product has the following accession number(s) (GI #11527402) (NCBI Accession #NP_068839.1) (Uniprot Accession #Q5W0A3). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Integral Membrane Protein 2B (ITM2B, BRICHOS Domain Containing 2B) with the following immunoassay(s):
Western Blot (WB) (Western Blot Test: E coli-derived fusion protein as test antigen. Affinity-Purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.)
ITM2B is a type II membrane protein. It is expressed in brain and in other tissues. Defects in ITM2B seem to be associated with familial British dementia (FBD) and familial Danish dementia (FDD).
Immunogen: Synthetic peptide corresponding to aa1-60. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ITM2B are readily searchable from our website. Different antibodies against the same target such as ITM2B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. ITM2B also interacts with the following gene(s): APP. Blood, Bone, Brain, Epididymis, Eye, Kidney, Muscle, Nerve, Testis, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Cardiovascular Diseases, Cataract, Dementia, familial British, Drug Toxicity, Hemorrhage, Neoplasms, Nervous System Diseases, Neurodegenerative Diseases, Tauopathies are some of the diseases may be linked to Integral Membrane Protein 2B (ITM2B, BRICHOS Domain Containing 2B).