anti-ITPKA antibody product blog
Tags: Antibody; Polyclonal Antibody; ITPKA; anti-ITPKA antibody; Inositol 1,4,5-trisphosphate 3-kinase A;
The ITPKA itpka (Catalog #MBS649144) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Inositol 1,4,5-trisphosphate 3-kinase A, NT (Inositol-trisphosphate 3-kinase A, InsP 3-kinase A, IP3 3-kinase A, IP3K A, IP3KA, IP3-3KA, ITPKA) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Inositol 1,4,5-trisphosphate 3-kinase A can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the ITPKA itpka for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ITPKA itpka product has the following accession number(s) (GI #4504789) (NCBI Accession #NP_002211.1) (Uniprot Accession #P23677). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Inositol 1,4,5-trisphosphate 3-kinase A, NT (Inositol-trisphosphate 3-kinase A, InsP 3-kinase A, IP3 3-kinase A, IP3K A, IP3KA, IP3-3KA, ITPKA) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of anti-ITPKA Antibody (N-term) in mouse cerebellum tissue lysates (35ug/lane). ITPKA(arrow) was detected using the purified Pab.)
ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
Immunogen: Synthetic peptide selected from the N-terminal region of human ITPKA (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ITPKA are readily searchable from our website. Different antibodies against the same target such as ITPKA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.