anti-JAK1 antibody product blog
Tags: Antibody; Polyclonal Antibody; JAK1; anti-JAK1 antibody;
The JAK1 jak1 (Catalog #MBS9205357) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAK1 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s JAK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:1000. Researchers should empirically determine the suitability of the JAK1 jak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The JAK1 jak1 product has the following accession number(s) (GI #102469034) (NCBI Accession #NP_002218.2) (Uniprot Accession #P23458). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JAK1 Antibody (C-term) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of lysates from HT-29 cell line and mouse spleen tissue lysate(from left to right), using JAK1 Antibody (C-term). MBS9205357 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
Function: Tyrosine kinase of the non-receptor type,involved in the IFN-alpha/beta/gamma signalpathway (PubMed: href="http://www.uniprot.org/citations/7615558"target="_blank">7615558). Kinase partner for the interleukin (IL)-2 receptor(PubMed:
Cellular Location: Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
Tissue Location: Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing JAK1 are readily searchable from our website. Different antibodies against the same target such as JAK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Brain, Heart, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. JAK1 also interacts with the following gene(s): IL2RB, IRS1, PTPN11, SOCS3, STAT1, STAT2, STAT3, STAT5A, STAT5B, STAT6.