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anti-JAK2 antibody product blog

Posted on 2016-06-14 10:28:50 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; JAK2; anti-JAK2 antibody;
The JAK2 jak2 (Catalog #MBS2526246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAK2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s JAK2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).
IHC: 1:50-1:200. Researchers should empirically determine the suitability of the JAK2 jak2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The JAK2 jak2 product has the following accession number(s) (GI #3236322) (NCBI Accession #AAC23653.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JAK2 Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain tissue using JAK2 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC) JAK2.

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using JAK2 Polyclonal Antibody at dilution 1:35)
Immunohistochemistry (IHC) JAK2.

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Immunogen: Synthetic peptide of human JAK2. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing JAK2 are readily searchable from our website. Different antibodies against the same target such as JAK2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. JAK2 also interacts with the following gene(s): CSF2RB, EPOR, GHR, PRLR, PTPN11, SH2B1, SOCS1, SOCS3, STAT1, STAT3. Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Muscle, Skin, Spleen, Vascular tissues are correlated with this protein. Cardiovascular Diseases, Inflammation, Leukemia, Leukemia, Myeloid, Acute, Myeloproliferative Disorders, Polycythemia, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, Thrombocytosis are some of the diseases may be linked to JAK2 Polyclonal Antibody.
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