anti-JAM-B antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-JAM-B antibody; JAM-B;
The JAM-B jam2 (Catalog #MBS9402862) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAM-B antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s JAM-B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250. Researchers should empirically determine the suitability of the JAM-B jam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The JAM-B jam2 product has the following accession number(s) (GI #10864029) (NCBI Accession #NP_067042). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JAM-B antibody with the following immunoassay(s):
Testing Data (Sample (30 ug of whole cell lysate)A: A431 12 % SDS PAGEPrimary antibody diluted at 1: 1000)
Immunohistochemistry (IHC) (A:Immunohistochemical analysis of paraffin-embedded TOV-112D xenograft, using JAM-B antibody at 1: 100 dilution. B:Immunohistochemical analysis of paraffin-embedded human colon, using JAM-B antibody at 1: 200 dilution. C:Immunohistochemical analysis of paraffin-embedded mouse small intestine, using JAM-B antibody at 1: 200 dilution.)
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq].
Immunogen Type: Recombinant protein
Immunogen Description: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 264 of Human JAM2. Target Name: JAM-B. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing JAM-B are readily searchable from our website. Different antibodies against the same target such as JAM-B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Ear, Embryonic Tissue, Eye, Intestine, Kidney, Lung, Nerve, Testis tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Cell Transformation, Neoplastic, Infertility, Male, Inflammation, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Neurobehavioral Manifestations are some of the diseases may be linked to JAM-B antibody.