anti-JUP antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-JUP antibody; JUP;
The JUP jup (Catalog #MBS7003467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JUP Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s JUP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the JUP jup for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The JUP jup product has the following accession number(s) (GI #4504811) (NCBI Accession #NP_002221.1) (Uniprot Accession #P14923). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JUP Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot
All lanes: JUP antibody at 2ug/ml+A431 cells
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 82kDa
Observed band size: 82kDa
)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human breast cancer using MBS7003467 at dilution 1:100)
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
Immunogen: Recombinant human Junction plakoglobin protrin. Conjugation: Non-conjugated
Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30997 / sc-30996 / sc-30998 / sc-7900 / sc-1497-R. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing JUP are readily searchable from our website. Different antibodies against the same target such as JUP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Heart, Kidney, Liver, Lung, Lymph, Lymph Node, Mouth, Muscle, Skin tissues are correlated with this protein.