|The KAPCB prkacb (Catalog #MBS9406084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KAPCB Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KAPCB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the KAPCB prkacb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KAPCB prkacb product has the following accession number(s) (GI #338827753) (NCBI Accession #NP_001229786.1) (Uniprot Accession #P22694). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KAPCB Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from Jurkat cells and COLO205 cells, using KAPCB antibody.)
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.Beebe S.J., Mol. Endocrinol. 4:465-475(1990).Gregory S.G., Nature 441:315-321(2006).Wu K.-J., Oncogene 21:7872-7882(2002).
Immunogen Type: Peptide
Immunogen Description: Synthesized peptide derived from internal of human KAPCB. Target Name: KAPCB. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KAPCB are readily searchable from our website. Different antibodies against the same target such as KAPCB may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. KAPCB also interacts with the following gene(s): PRKACA, PRKAR1A, PRKAR2A, PRKAR2B. Blood, Brain, Embryonic Tissue, Heart, Liver, Lung, Nerve, Skin, Stomach tissues are correlated with this protein. Brain Diseases, Breast Neoplasms, Carcinoma, Hepatocellular, Depressive Disorder, Embryo Loss, Heart Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Nervous System Diseases are some of the diseases may be linked to KAPCB Antibody.