anti-KCNK12 antibody product blog
Tags: Antibody; Polyclonal Antibody; KCNK12; anti-KCNK12 antibody;
The KCNK12 kcnk12 (Catalog #MBS150598) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNK12 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KCNK12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).KCNK12 antibody can be used for detection of KCNK12 by Western blot at 0.5 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the KCNK12 kcnk12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KCNK12 kcnk12 product has the following accession number(s) (GI #11545761) (NCBI Accession #NP_071338) (Uniprot Accession #Q9HB15). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KCNK12 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of KCNK12 in rat brain tissue lysate with KCNK12 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC) (Immunohistochemistry of KCNK12 in mouse brain tissue with KCNK12 antibody at 5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of KCNK12 in mouse brain tissue with KCNK12 antibody at 20 μg/mL.)
KCNK12 Antibody: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.
Conjugate: Unconjugated
Immunogen: KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12.
Buffer: KCNK12 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KCNK12 are readily searchable from our website. Different antibodies against the same target such as KCNK12 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.