|The KIDINS220 kidins220 (Catalog #MBS536058) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Kidins220 antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Kidins220 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the KIDINS220 kidins220 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KIDINS220 kidins220 product has the following accession number(s) (GI #55741641) (NCBI Accession #NP_065789.1) (Uniprot Accession #Q9ULH0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Affinity purified Rabbit polyclonal Kidins220 antibody.
Biological Significance: A novel protein kinase D-interacting substrate of 220 kDa (Kidins220) or ARMS is the first identified Protein kinase D (PkDa), a serine/threonine kinase. Kidins220 is an integral membrane protein that is expressed in brain and neuroendocrine cells. Kidins220 is phsphorylated by PkDa at serine 919 in vivo. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Kidins220 antibody was raised in rabbit using residues 1747-1762 [ASSESTGFGEERESIL] of the human 220kDa Kidins220 protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KIDINS220 are readily searchable from our website. Different antibodies against the same target such as KIDINS220 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Inflammation, Learning Disorders, Memory Disorders, Necrosis, Nerve Degeneration, Weight Loss are some of the diseases may be linked to Kidins220 antibody. Blood, Brain, Embryonic Tissue, Eye, Heart, Lung, Nerve, Skin, Spleen, Vascular tissues are correlated with this protein. KIDINS220 also interacts with the following gene(s): BRAF, CRKL, NGF. The following patways have been known to be associated with this gene.