anti-KIR2DL5A antibody product blog
Tags: Antibody; Polyclonal Antibody; KIR2DL5; anti-KIR2DL5A antibody; KIR2DL5A;
The KIR2DL5A kir2dl5a (Catalog #MBS647395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIR2DL5 (Killer Cell Immunoglobulin-like Receptor 2DL5A, CD158f1, KIR2DL5A, CD158F, CD158F1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s KIR2DL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot. Researchers should empirically determine the suitability of the KIR2DL5A kir2dl5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KIR2DL5A kir2dl5a product has the following accession number(s) (GI #11968154) (NCBI Accession #NP_065396.1) (Uniprot Accession #Q8N109). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MSLMVISMAC VGFFLLQGAW THEGGQDKPL LSAWPSAVVP RGGHVTLLCR SRLGFTIFSL YKEDGVPVPE LYNKIFWKSI LMGPVTPAHA GTYRCRGSHP RSPIEWSAPS NPLVIVVTGL FGKPSLSAQP GPTVRTGENV TLSCSSRSSF DMYHLSREGR AHEPRLPAVP SVNGTFQADF PLGPATHGGT YTCFGSLHDS PYEWSDPSDP LLVSVTGNSS SSSSSPTEPS SKTGIRRHLH ILIGTSVAII LFIILFFFLL HCCCSNKKNA AVMDQEPAGD RTVNREDSDD QDPQEVTYAQ LDHCVFTQTK ITSPSQRPKT PPTDTTMYME LPNAKPRSLS PAHKHHSQAL RGSSRETTAL SQNRVASSHV PAAGI.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KIR2DL5 (Killer Cell Immunoglobulin-like Receptor 2DL5A, CD158f1, KIR2DL5A, CD158F, CD158F1) with the following immunoassay(s):
Western Blot (WB) (Western Blot analysis of KIR2DL5A expression in transfected 293T cell line by KIR2DL5A polyclonal antibody. Lane 1: KIR2DL5A transfected lysate (41.25kD). Lane 2: Non-transfected lysate.)
KIR2DL5 is the most recently identified human killer cell immunoglobulin-like receptors (KIR), which are transmembrane glycoproteins expressed by natural killer cells (NK) and subsets of T cells. KIR2DL5 is a type II member of the KIR2D family with two extracellular Ig-like domains of the D0 and D2 type. Its structure is expressed by 50% of humans and is conserved among primate species. Its gene localized on human chromosome 19p13.3, is restricted to the B subset of KIR haplotypes. The protein is represented in the human genome by two genes, KIR2DL5A and KIR2DL5B that show 99.5-99.7% identity in their coding sequences. The protein acts as a receptor on NK cells for HLA-C alleles, inhibits the activity of NK cell and thus plays a specialized role in innate immunity.
Immunogen: Full length human KIR2DL5A, aa1-375 (AAI60063.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KIR2DL5A are readily searchable from our website. Different antibodies against the same target such as KIR2DL5A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.