|The KIT kit (Catalog #MBS9211970) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-KIT (Y730) Antibody reacts with Human (Predicted Reactivity: Bovine, Pig) and may cross-react with other species as described in the data sheet. MyBioSource\'s Phospho-KIT (Y730) can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), ELISA (EIA).
DB~~1:500. Researchers should empirically determine the suitability of the KIT kit for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KIT kit product has the following accession number(s) (GI #4557695) (NCBI Accession #NP_000213.1) (Uniprot Accession #P10721). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Phospho-KIT (Y730) Antibody with the following immunoassay(s):
Dot Blot (DB) (Dot blot analysis of Phospho-KIT-Y730 Antibody Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.)
This gene encodes the human homolog of the proto-oncogene
c-kit. C-kit was first identified as the cellular homolog of the
feline sarcoma viral oncogene v-kit. This protein is a type 3
transmembrane receptor for MGF (mast cell growth factor, also known
as stem cell factor). Mutations in this gene are associated with
gastrointestinal stromal tumors, mast cell disease, acute
myelogenous lukemia, and piebaldism. Multiple transcript variants
encoding different isoforms have been found for this gene.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KIT are readily searchable from our website. Different antibodies against the same target such as KIT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. KIT also interacts with the following gene(s): DOK1, EPOR, GRB2, KITLG, PIK3CG, PIK3R1, PTPN11, SOCS6, STAT1, STAT5B. Brain, Heart, Intestine, Kidney, Liver, Lung, Muscle, Nerve, Skin, Spleen tissues are correlated with this protein. Breast Neoplasms, Gastrointestinal Stromal Tumors, Heart Diseases, Inflammation, Leukemia, Myeloid, Acute, Liver Diseases, Lung Diseases, Lung Neoplasms, Necrosis, Nervous System Diseases are some of the diseases may be linked to Phospho-KIT (Y730) Antibody.