anti-KLHL1 antibody product blog
Tags: Antibody; Polyclonal Antibody; KLHL1; anti-KLHL1 antibody;
The KLHL1 klhl1 (Catalog #MBS150234) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLHL1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KLHL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).KLHL1 antibody can be used for the detection of KLHL1 by Western blot at 2 - 4 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. Researchers should empirically determine the suitability of the KLHL1 klhl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KLHL1 klhl1 product has the following accession number(s) (GI #8926179) (NCBI Accession #AAF81719) (Uniprot Accession #Q9NR64). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KLHL1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of KLHL1 in HeLa cell lysate with KLHL1 antibody at (A) 2 and (B) 4 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 μg/mL.)
KLHL1 Antibody: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
Conjugate: Unconjugated
Immunogen: KLHL1 antibody was raised against a 14 amino acid synthetic peptide from near the amino-terminus of human KLHL1.
Buffer: KLHL1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KLHL1 are readily searchable from our website. Different antibodies against the same target such as KLHL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.