|The KPNA3 kpna3 (Catalog #MBS241959) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human KPNA3 / Importin Alpha 4 reacts with Bat, Gibbon, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KPNA3 / Importin Alpha 4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).
ELISA, IHC-P (5 ug/ml), WB (0.1 - 0.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the KPNA3 kpna3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KPNA3 kpna3 product has the following accession number(s) (GI #34485722) (NCBI Accession #NP_002258.2) (Uniprot Accession #O00505). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat Polyclonal to Human KPNA3 / Importin Alpha 4 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-KPNA3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB) (Antibody staining (0.1 ug/ml) of Human Testis lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.)
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs).
Target Species: Human
Immunogen Description: Synthetic peptide C-DPTANLQTKEFNF from the C-terminus of human KPNA3 (NP_002258.2). Immunogen Type: Synthetic peptide
Immunogen: KPNA3 / Importin Alpha 4 antibody was raised against synthetic peptide C-DPTANLQTKEFNF from the C-terminus of human KPNA3 (NP_002258.2). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard (100%); Xenopus (85%).
Antigen Modification: C-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KPNA3 are readily searchable from our website. Different antibodies against the same target such as KPNA3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.