anti-KRT6A/KRT6B/KRT6C antibody product blog
Tags: Antibody; Polyclonal Antibody; KRT6A/KRT6B/KRT6C; anti-KRT6A/KRT6B/KRT6C antibody;
The KRT6A/KRT6B/KRT6C n/a (Catalog #MBS2522848) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KRT6A/KRT6B/KRT6C Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KRT6A/KRT6B/KRT6C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).IHC: 1:25-1:100. Researchers should empirically determine the suitability of the KRT6A/KRT6B/KRT6C n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the KRT6A/KRT6B/KRT6C Polyclonal Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using KRT6A/KRT6B/KRT6C Polyclonal Antibody at dilution 1:40)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using KRT6A/KRT6B/KRT6C Polyclonal Antibody at dilution 1:40)
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Immunogen: Synthetic peptide of human KRT6A/KRT6B/KRT6C. Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KRT6A/KRT6B/KRT6C are readily searchable from our website. Different antibodies against the same target such as KRT6A/KRT6B/KRT6C may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.