Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Polyclonal Antibody Blog  rightarrow anti-LIMK1 antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-PSMF1 antibody blog
 • anti-SLC7A10 antibody blog
 • anti-Erk1,2 antibody blog
 • anti-NT5E antibody blog
 • anti-CAMK2G antibody blog
 • anti-STS antibody blog
 • anti-C2orf49 antibody blog
 • anti-MARK2 antibody blog
 • anti-MCSP antibody blog
 • anti-FABP antibody blog
 • anti-SATB1 antibody blog
 • anti-FGFR4 antibody blog
 • anti-HIV-1 antibody blog
 • anti-BIRC2 antibody blog
 • anti-FSD1 antibody blog
 • anti-OAS1 antibody blog
 • anti-p53DINP1 antibody blog
 • anti-SNAP25 antibody blog
 • anti-IFNGR1 antibody blog
 • anti-GCDFP15 antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • MURF1-TRIM63 Antibody
 • Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) ELISA Kit
 • Amylase (AMY2A) Antibody
 • ADAMTS15 Antibody
 • anti-Protein G Antibody
 • CML (Carboxymethyl-lysine) Antibody
 • 5'-AMP-activated protein kinase subunit gamma-3 (Prkag3) Recombinant Protein
 • AKT2 Recombinant Protein
 • Calsequestrin-1 (CASQ1) Recombinant Protein
 • Actin, Alpha cardiac muscle 1 (ACTC1) ELISA Kit
 • Uracil DNA Glycosilase (UNG) Antibody
 • Insulin Like Growth Factor Binding Protein 5 (IGFBP5) Antibody
 • prenylcysteine oxidase 1 (PCYOX1) Antibody
 downarrow more ...

anti-LIMK1 antibody product blog

Posted on 2015-07-20 12:40:38 by mybiosource_staff
Share it on ...     
Tags: Antibody; Polyclonal Antibody; LIMK1; anti-LIMK1 antibody; LIMK1 (C-terminus);
The LIMK1 limk1 (Catalog #MBS472032) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIMK1 (C-terminus) reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s LIMK1 (C-terminus) can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot.
ELISA: 1:2000
Western Blot: 1:1000. Researchers should empirically determine the suitability of the LIMK1 limk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The LIMK1 limk1 product has the following accession number(s) (GI #4505001) (NCBI Accession #NP_002305.1) (Uniprot Accession #P53667). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the LIMK1 (C-terminus) with the following immunoassay(s):
Testing Data
Testing Data LIMK1.

LIM kinases (LIMK1 and LIMK2) are serine/threonine kinases that have two zinc finger motifs, known as LIM motifs, in their amino-terminal regulatory domains. LIM kinases are involved in actin cytoskeletal regulation downstream of Rho-family GTPases, PAKs, and ROCK. PAK1 and ROCK phosphorylate LIMK1 or LIMK2 at the conserved Thr-508 or Thr-505 residues in the activation loop, increasing LIMK activity. In addition, VEGF-induced stress fiber formation has been linked to p38- mediated activation of LIMK through MK-2 phosphorylation of Ser-323. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the amino-terminal Ser-3 residue of cofilin. In addition, LIMKs may have a function in the nucleus. It has been shown that the nuclear localization of LIMKs can mediate suppression of Rac/Cdc42-mediated cyclin D1 expression. This effect of LIMKs was independent of cofilin phosphorylation and the regulation of actin dynamics.

Immunogen: LIMK1 (C-terminus) synthetic peptide (coupled to carrier protein) corresponding to amino acids at the C-terminus of human LIMK1. This sequence is conserved in rat and mouse LIMK1, and is not found in LIMK2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LIMK1 are readily searchable from our website. Different antibodies against the same target such as LIMK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions