|The LTB4R ltb4r (Catalog #MBS244534) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human Leukotriene B4 Receptor / BLT1 reacts with Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Rat, Hamster, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s Leukotriene B4 Receptor / BLT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (20 ug/ml). Researchers should empirically determine the suitability of the LTB4R ltb4r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LTB4R ltb4r product has the following accession number(s) (GI #221218998) (NCBI Accession #NP_001137391.1) (Uniprot Accession #Q15722). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human Leukotriene B4 Receptor / BLT1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-Leukotriene B4 Receptor antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997). Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor (Yokomizo et al., 1997).
Target Species: Human
Immunogen Description: Synthetic 20 amino acid peptide from 1st cytoplasmic domain of human Leukotriene B4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Rat, Rabbit (95%); Monkey, Mouse, Hamster (90%). Immunogen Type: Synthetic peptide
Immunogen: Leukotriene B4 Receptor / BLT1 antibody was raised against synthetic 20 amino acid peptide from 1st cytoplasmic domain of human Leukotriene B4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Rat, Rabbit (95%); Monkey, Mouse, Hamster (90%).
Antigen Modification: Cytoplasmic Domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LTB4R are readily searchable from our website. Different antibodies against the same target such as LTB4R may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.