anti-LTF antibody product blog
Tags: Antibody; Lactoferrin; Polyclonal Antibody; LTF; anti-LTF antibody;
The LTF ltf (Catalog #MBS584469) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lactoferrin, Bovine, pAb reacts with Bovine and may cross-react with other species as described in the data sheet. MyBioSource\'s Lactoferrin can be used in a range of immunoassay formats including, but not limited to, Immunoassay (IA), Immunopreciptation (IP), Western Blot (WB).. Researchers should empirically determine the suitability of the LTF ltf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LTF ltf product has the following accession number(s) (GI #2104522) (NCBI Accession #AAB57795.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Product Description: Lactoferrin is an approximately 80 kDa glycoprotein which was first isolated from milk and found in epithelia and most body fluids and secretions. Lactoferrin is secreted in plasma by neutrophils. Its plasma concentration represents a positive relation to the total pool of neutrophils and the rate of neutrophil turnover. In inflammation lactoferrin is released from secondary granules of neutrophilic leukocytes into the extracellular medium. Therefore the extracellular lactoferrin concentration can be used as an index for neutrophil activation.
Lactoferrin is able to strongly bind to iron and considered to have antibacterial properties. Human lactoferrin binds to bacterial products through its highly positively charged N terminus and kills various bacteria most probably by inducing intracellular changes in these bacteria without affecting the membrane permeability. Lactoferrin also plays a role in signal transduction, immunomodulation and has antiadhesive, anticancer, antiviral activity.
In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LTF are readily searchable from our website. Different antibodies against the same target such as LTF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Cardiovascular Diseases, Heart Diseases, Hypertension, Immune System Diseases, Inflammation, Lung Diseases, Necrosis, Nervous System Diseases, Vascular Diseases are some of the diseases may be linked to Lactoferrin, Bovine, pAb.