anti-MAK10 antibody product blog
Tags: Antibody; Polyclonal Antibody; MAK10; anti-MAK10 antibody;
The MAK10 naa35 (Catalog #MBS150477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAK10 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MAK10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).MAK10 antibody can be used for detection of MAK10 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the MAK10 naa35 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MAK10 naa35 product has the following accession number(s) (GI #145275204) (NCBI Accession #NP_078911) (Uniprot Accession #Q5VZE5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MAK10 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of MAK10 in mouse heart tissue lysate with MAK10 antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of MAK10 in human heart tissue with MAK10 antibody at 5 μg/mL.)
MAK10 Antibody: The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
Conjugate: Unconjugated
Immunogen: MAK10 antibody was raised against a 14 amino acid synthetic peptide near the center of human MAK10.
Buffer: MAK10 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MAK10 are readily searchable from our website. Different antibodies against the same target such as MAK10 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.