|The Man1c1 n/a (Catalog #MBS646486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAN1C1 (Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC, HMIC, Mannosidase alpha Class 1C Member 1, Processing alpha-1,2-mannosidase IC, Alpha-1,2-mannosidase IC, MAN1A3, MAN1C) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MAN1C1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Suitable for use in Western Blot. Researchers should empirically determine the suitability of the Man1c1 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Man1c1 n/a product has the following accession number(s) (GI #20988942) (NCBI Accession #AAH30443.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MLMRKVPGFV PASPWGLRLP QKFLFLLFLS GLVTLCFGAL FLLPHSSRLK RLFLAPRTQQ PGLEVVAEIA GHAPAREQEP PPNPAPAAPA PGEDDPSSWA SPRRRKGGLR RTRPTGPREE ATAARGNSIP ASRPGDEGVP FRFDFNAFRS RLRHPVLGTR ADESQEPQSQ VRAQREKIKE MMQFAWQSYK RYAMGKNELR PLTKDGYEGN MFGGLSGATV IDSLDTLYLM ELKEEFQEAK AWVGESFHLN VSGEASLFEV NIRYIGGLLS AFYLTGEEVF RIKAIRLGEK LLPAFNTPTG IPKGVVSFKS GNWGWATAGS SSILAEFGSL HLEFLHLTEL SGNQVFAEKV RNIRKVLRKI EKPFGLYPNF LSPVSGNWVQ HHVSVGGLGD SFYEYLIKSW LMSGKTDMEA KNMYYEALEA IETYLLNVSP GGLTYIAEWR GGILDHKMGH LACFSGGMIA LGAEDAKEEK RAHYRELAAQ ITKTCHESYA RSDTKLGPEA FWFNSGREAV ATQLSESYYI LRPEVVESYM YLWRQTHNPI YREWGWEVVL ALEKYCRTEA GFSGIQDVYS STPNHDNKQQ SFFLAETLKY LYLLFSEDDL LSLEDWVFNT EAHPLPVNHS DSSGRAWGRH.
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MAN1C1 belongs to the glycosyl hydrolase 47 family. It is involved in the maturation of Asn-linked oligosaccharides. It trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. MAN1C1 is expressed in most tissues with the exception of lung, muscle and pancreas. It is highly expressed in placenta.
Immunogen: Full length human MAN1C1, aa1-630 (NP_065112.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Man1c1 are readily searchable from our website. Different antibodies against the same target such as Man1c1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.