anti-MAPK14 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-MAPK14 antibody; MAPK14; MAP Kinase 14;
The MAPK14 mapk14 (Catalog #MBS625691) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAP Kinase 14, phosphorylated (Thr180) (Mitogen-activated Protein Kinase 14, MAPK 14, MAPK14, Mitogen-activated Protein Kinase p38alpha, MAP Kinase p38alpha, Cytokine Suppressive Anti-inflammatory Drug Binding Protein, CSAID Binding Protein, CSBP, MAX-int reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s MAP Kinase 14 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry:1:50-1:100. Researchers should empirically determine the suitability of the MAPK14 mapk14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MAPK14 mapk14 product has the following accession number(s) (GI #49168496) (Uniprot Accession #Q16539). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38a, p38b and p38g, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38, p38 and p38 are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Immunogen: Synthetic phosphopeptide corresponding to human MAP Kinase, p38 around the phosphorylation site of threonine 180 (E-M-TP-G-Y). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MAPK14 are readily searchable from our website. Different antibodies against the same target such as MAPK14 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arthritis, Rheumatoid, Autoimmune Diseases, Cardiovascular Diseases, Central Nervous System Diseases, Death, Heart Diseases, Inflammation, Necrosis, Neoplasms, Vascular Diseases are some of the diseases may be linked to MAP Kinase 14, phosphorylated (Thr180) (Mitogen-activated Protein Kinase 14, MAPK 14, MAPK14, Mitogen-activated Protein Kinase p38alpha, MAP Kinase p38alpha, Cytokine Suppressive Anti-inflammatory Drug Binding Protein, CSAID Binding Protein, CSBP, MAX-int.