anti-MARK1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-MARK1 antibody; MARK1;
The MARK1 mark1 (Catalog #MBS9402469) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MARK1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s MARK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the MARK1 mark1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MARK1 mark1 product has the following accession number(s) (GI #554790379) (NCBI Accession #NP_001273057.1) (Uniprot Accession #Q9P0L2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MARK1 Antibody with the following immunoassay(s):
Testing Data (Gel: 6%SDS-PAGE Lysates (from left to right): Mouse brain tissue Amount of lysate: 40ug per lane Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/30.)
MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
Immunogen Type: Recombinant Protein
Immunogen Description: Fusion protein corresponding to residues near the C terminal of human MAP/microtubule affinity-regulating kinase 1
SDS-PAGE MW: 89 kd. Target Name: MARK1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MARK1 are readily searchable from our website. Different antibodies against the same target such as MARK1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Inflammation, Liver Diseases, Lung Neoplasms, Necrosis, Nervous System Diseases, Stomach Neoplasms, Vascular Diseases are some of the diseases may be linked to MARK1 Antibody. Brain, Embryonic Tissue, Eye, Heart, Intestine, Kidney, Lung, Nerve, Skin, Stomach tissues are correlated with this protein.