Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Polyclonal Antibody Blog  rightarrow anti-MAVS antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-VASP antibody blog
 • anti-MARCKS antibody blog
 • anti-BCL2 antibody blog
 • anti-NFYB antibody blog
 • anti-FASTKD2 antibody blog
 • anti-OCRL antibody blog
 • anti-METTL6 antibody blog
 • anti-GLRA1 antibody blog
 • anti-APOA1BP antibody blog
 • anti-ACOX3 antibody blog
 • anti-BANK1 antibody blog
 • anti-GANC antibody blog
 • anti-UCP1 antibody blog
 • anti-DIAPH3 antibody blog
 • anti-AATK antibody blog
 • anti-SELL antibody blog
 • anti-STK11 antibody blog
 • anti-SLC22A17 antibody blog
 • anti-POU class 4 homeobox 2 antibody blog
 • anti-NLGN4Y antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • BAG3 cDNA Clone
 • Heterogeneous nuclear ribonucleoproteins A2-B1 (HNRNPA2B1) Recombinant Protein
 • IGF1 Receptor (IGF1R) Blocking Peptide
 • CD45 Antibody
 • KAP1 - TRIM28 Peptide
 • H-2KdDd Antibody
 • IGF-1 ELISA Kit
 • CD40 Antibody
 • Galectin-1 (LGALS1) Recombinant Protein
 • Soluble Terminal Complement Complex (SC5B-9) ELISA Kit
 • R-Spondin 1 (RSPO1) ELISA Kit
 downarrow more ...

anti-MAVS antibody product blog

Posted on 2016-02-02 14:07:13 by mybiosource_staff
Share it on ...     
Tags: Antibody; Polyclonal Antibody; anti-MAVS antibody; MAVS; mitochondrial antiviral signaling protein;
The MAVS mavs (Catalog #MBS610711) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mitochondrial Antiviral Signaling Protein (MAVS, VISA) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Mitochondrial Antiviral Signaling Protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF).
Dilution: Western Blot: 1:1000
Immunofluorescence (IF-IC): 1:50. Researchers should empirically determine the suitability of the MAVS mavs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The MAVS mavs product has the following accession number(s) (GI #83776598) (NCBI Accession #NP_065797.2) (Uniprot Accession #Q7Z434). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

The mitochondrial antiviral signaling protein (MAVS, VISA) contributes to innate immunity by triggering IRF-3 and NF- B activation in response to viral infection, leading to the production of IFN- (1). The MAVS protein contains an N-terminal CARD domain and a C-terminal mitochondrial transmembrane domain. The MAVS adaptor protein plays a critical and specific role in viral defenses (2). MAVS acts downstream of the RIG-I RNA helicase and viral RNA sensor, leading to the recruitment of IKK, TRIF and TRAF6 (3,4). Some viruses have evolved strategies to circumvent these innate defenses by using proteases that cleave MAVS to prevent its mitochondrial localization (5,6).

MAVS mavs

Immunogen: Synthetic peptide (KLH-coupled) corresponding to residues at the carboxyl terminus of human MAVS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MAVS are readily searchable from our website. Different antibodies against the same target such as MAVS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Heart, Kidney, Liver, Lung, Muscle, Nerve, Spleen, Vascular tissues are correlated with this protein. Anemia, Congenital Abnormalities, Fibrosis, Hemorrhage, Hypertension, Inflammation, Liver Neoplasms, Lung Neoplasms, Myocardial Ischemia, Nervous System Malformations are some of the diseases may be linked to Mitochondrial Antiviral Signaling Protein (MAVS, VISA). MAVS also interacts with the following gene(s): DDX58, IRF3, IRF7, TBK1, TRAF6. The following patways have been known to be associated with this gene.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions